– Simply activate with cold water! – Lightweight and compact – Reusable All FRIO bags are designed with our patented crystal technology to keep your temperature-sensitive medications cool and safe. The FRIO bag is perfect for insulin vials or cartridges as well as auto-injectors. This makes this FRIO ideal for patients with conditions such as diabetes, rheumatoid arthritis, Crohn's disease and anaphylaxis. With a continuous cooling time of at least 45 hours and a charging time of less than 5 minutes, FRIO is just right for your everyday life – wherever that may be! FRIO bag not right for you? FRIO is available in a variety of sizes. If you'd like to store something else in your FRIO, just browse our shop to find your FRIO.